From my house, if I have to go into town, it's about a 5-10 mile drive depending on where I'm going, and mostly uphill with a number of stoplights. My vehicle usually reports about 15-17 MPG for that short trip.
On the return trip, same distance but mostly downhill, the LC will ready 18-20 MPG.
Once a week I have to drive into a remote office for work, ~55 mile trip one way on the highway... vehicle usually reports 24-26 MPG for that trip.
I'm riding on KO3 245/70R18 ("C" range), so they're lighter than your "E" range KO3s, but the point remains, the vehicle is much closer to advertised MPG on the highway...fortunately for me, that's the majority of my driving these days.