EDIT: I've only driven the 24 not the 19-23 model years but most of this is applicable.
I've had the luxury of driving both for several days (well the cayenne was a non-s and non-hybrid). I think the LC is a better value and better experience. However, If you value traveling at 80-95MPH over long journeys the LC is probably not the best fit as its not as comfortable at those speeds. The LC is a box on top of a brick whereas the Porsche is designed for high speed stability and handling. The Toyota feels more comfortable day to day but if you drive fast that will negate the comfort.
With Porsche you're paying for the brand, customization, dealer experience, and German engineering whereas with the Toyota you're paying for a truck, that will hopefully be reliable

, and the off road bells and whistles. The Porsche will depreciate much faster and be more expensive to service, expect to be bent over when you trade it in...
If, when you go out on trips, you find yourself needing to bring everything and everyone its hard to beat the LC since it has so much more room. The load heigh of the LC is not ergonomic so if you need to put something really heavy in the back it could be tricky but its tall enough that you can fit a lot of crap in the back.
The differences that stood out to me the most were the visibility, interior, and the options/tech. The Cayenne seemed like it had terrible visibility, the hood is so tall and the visibility out the sides was not great. I relied on the cameras to park it. I much prefer the LC with its big side windows even though it also has a tall hood and large blind spots.
The interior of the Porsche is excellent but on par with the LC with premium pkg. The Porsche has touchscreens for everything and they are annoying, like there's an apple track-pad like interface with haptic feedback for the AC/seats which is weird. also, THERE IS TOO MUCH PIANO BLACK PLASTIC. The tech is similar but you'll pay an arm and a leg to get all the bells and whistles on the Porsch. Porsche probably has a better sound system but it should for how much more it costs.
If you drive fast, take corners fast, like lighting money on fire, and want brand cache get a porsche or any other unibody SUV.